Paraldehyde
Paraldehyde: High-Quality Pharmaceutical Solution
Paraldehyde is a cyclic ether that has been widely used in medical applications for its sedative and hypnotic properties. Our pharmaceutical-grade Paraldehyde meets the highest industry standards, providing reliable performance for various therapeutic applications.
Key Specifications of Paraldehyde
- Chemical Name: 2,4,6-Trimethyl-1,3,5-trioxane
- CAS Number: 123-63-7
- Molecular Formula: C6H12O3
- Molecular Weight: 132.16 g/mol
- Appearance: Colorless to pale yellow liquid
- Odor: Strong, characteristic pungent odor
- Boiling Point: 124°C (255°F)
- Melting Point: 12.6°C (54.7°F)
- Density: 0.994 g/cm³ at 25°C
- Flash Point: 36°C (97°F)
- Solubility: Miscible with water, alcohol, ether, chloroform
Technical Specifications
| Parameter | Specification | Testing Method |
|---|---|---|
| Purity | ≥99.5% | GC |
| Water Content | ≤0.2% | Karl Fischer |
| Acidity | ≤0.05% (as acetic acid) | Titration |
| Residue on Evaporation | ≤0.01% | Gravimetric |
| Refractive Index | 1.404-1.406 at 20°C | Refractometer |
| Heavy Metals | ≤10 ppm | ICP-MS |
Packaging Options for Paraldehyde
| Package Type | Volume | Material | Special Features |
|---|---|---|---|
| Amber Glass Bottles | 100ml | Type I glass | Teflon-lined caps |
| Amber Glass Bottles | 500ml | Type I glass | Teflon-lined caps |
| HDPE Bottles | 1L | High-density polyethylene | Child-resistant caps |
| HDPE Jerry Cans | 5L | High-density polyethylene | UN-certified |
| Steel Drums | 25L | Stainless steel | UN-certified |
Frequently Asked Questions About Paraldehyde
Medical Applications
Q: What are the primary medical uses of Paraldehyde?
A: Paraldehyde is primarily used as a sedative and anticonvulsant, particularly for managing acute episodes of agitation and seizures when other medications are ineffective or contraindicated. It has been historically used for treating alcohol withdrawal symptoms, tetanus, and epilepsy. Paraldehyde works by depressing the central nervous system through GABA receptor modulation.
Q: How is Paraldehyde administered in medical settings?
A: Paraldehyde can be administered via three routes: intramuscular injection, rectal administration, or oral use (though this is less common due to gastrointestinal irritation). The typical dose ranges from 5-10ml for adults, but must be precisely calculated based on body weight and condition severity. It's important to note that Paraldehyde should always be administered under medical supervision due to its potent effects.
Safety and Handling
Q: What safety precautions should be taken when handling Paraldehyde?
A: Paraldehyde requires careful handling due to its flammability and potential health effects. Key precautions include: working in well-ventilated areas, wearing appropriate PPE (gloves, goggles, lab coat), avoiding open flames or sparks, storing in tightly sealed containers away from light and heat, and having proper fire extinguishers (alcohol-resistant foam or CO2) nearby. Exposure can cause respiratory irritation, dizziness, or central nervous system depression.
Additional Information About Paraldehyde
Paraldehyde was first synthesized in 1829 and introduced into medical practice in 1882. Its unique chemical structure (a cyclic trimer of acetaldehyde) gives it distinct pharmacological properties that differ from other sedatives. While its use has declined with the development of newer medications, Paraldehyde remains an important option in specific clinical situations.
When stored properly in sealed amber containers away from light and heat sources, Paraldehyde maintains excellent stability. However, exposure to air can lead to oxidation, forming acetic acid, which increases product acidity and may reduce effectiveness. Proper storage is therefore crucial for maintaining product quality.
For research and specialized medical applications, our high-purity Paraldehyde offers consistent performance. Each batch undergoes rigorous quality control testing to ensure compliance with pharmacopeial standards. Our manufacturing process follows strict GMP guidelines to guarantee product safety and efficacy.