Guanidine hydrochloride

Premium Guanidine Hydrochloride for Industrial and Research Applications

Guanidine hydrochloride is a versatile chemical compound widely used in protein denaturation, nucleic acid purification, and various biochemical applications. Our high-purity Guanidine hydrochloride meets the stringent requirements of research laboratories and industrial processes.

Product Specifications

  • Chemical Formula: CH6ClN3
  • Molecular Weight: 95.53 g/mol
  • Appearance: White crystalline powder
  • Purity: ≥99% (ACS grade)
  • Solubility: Highly soluble in water (1080 g/L at 20°C)
  • pH: 4.5-6.0 (5% solution)
  • Melting Point: 180-185°C (with decomposition)

Technical Data Table

Parameter Specification Test Method
Assay (Titration) ≥99.0% ACS Method
Residue after Ignition ≤0.02% USP Method
Chloride Content 36.5-37.5% Ion Chromatography
Heavy Metals (as Pb) ≤5 ppm ICP-MS
Water Content ≤0.5% Karl Fischer

FAQ Section

What are the primary applications of Guanidine hydrochloride?

Guanidine hydrochloride is primarily used as a powerful protein denaturant in biochemical research. It's commonly employed in:

  • Protein unfolding studies
  • DNA/RNA extraction procedures
  • Chaotropic agent in chromatography
  • Solubilization of inclusion bodies
  • Virus inactivation processes
The strong denaturing properties make Guanidine hydrochloride particularly valuable in protein purification protocols.

How should Guanidine hydrochloride be stored?

Guanidine hydrochloride should be stored in a tightly closed container at room temperature (15-30°C) in a dry, well-ventilated area. While it's stable under normal conditions, it's recommended to:

  • Keep away from strong acids and bases
  • Avoid contact with oxidizing agents
  • Use within 3 years of manufacturing date for optimal performance
Proper storage maintains the stability and effectiveness of Guanidine hydrochloride for extended periods.

What safety precautions should be taken when handling Guanidine hydrochloride?

When working with Guanidine hydrochloride, always:

  • Wear appropriate PPE (gloves, lab coat, safety goggles)
  • Work in a fume hood when handling powdered form
  • Avoid inhalation of dust or mist
  • Wash thoroughly after handling
In case of contact with Guanidine hydrochloride, immediately flush eyes or skin with plenty of water for at least 15 minutes and seek medical attention if irritation persists.

Packaging Options

Package Size Container Type Unit Price
100g Plastic Bottle $XX.XX
500g Plastic Bottle $XX.XX
1kg Plastic Bottle $XX.XX
5kg Plastic Pail $XX.XX
25kg Fiber Drum $XX.XX

For bulk quantities of Guanidine hydrochloride beyond 25kg, please contact our sales department for custom pricing and packaging solutions. We offer competitive rates for research institutions and industrial users requiring large volumes.

Quality Assurance

Our Guanidine hydrochloride undergoes rigorous quality control testing to ensure:

  • Consistent purity across all batches
  • Low heavy metal content
  • Minimal water absorption
  • Optimal solubility characteristics
Each batch of Guanidine hydrochloride is accompanied by a comprehensive Certificate of Analysis documenting all quality parameters.

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