Sodium Salicylate
Sodium Salicylate is a widely used chemical compound with applications in pharmaceuticals, cosmetics, and industrial processes. As a sodium salt of salicylic acid, it offers excellent anti-inflammatory, analgesic, and antipyretic properties. Below is a detailed breakdown of its specifications, usage guidelines, and frequently asked questions.
Product Specifications
Sodium Salicylate is available in high-purity grades suitable for various applications. Here are the key parameters:
- Chemical Formula: C7H5NaO3
- Molecular Weight: 160.11 g/mol
- Appearance: White crystalline powder
- Solubility: Highly soluble in water and alcohol
- Melting Point: 200-210°C (392-410°F)
- Purity: ≥99.5%
- PH Value: 5.0-7.0 (5% aqueous solution)
| Parameter | Specification |
|---|---|
| Assay (HPLC) | ≥99.5% |
| Heavy Metals (as Pb) | ≤10 ppm |
| Chloride (Cl) | ≤0.01% |
| Sulfate (SO4) | ≤0.02% |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Frequently Asked Questions
Q: What are the primary uses of Sodium Salicylate?
A: Sodium Salicylate is primarily used as an analgesic and anti-inflammatory agent in pharmaceutical preparations. It's also used in cosmetics as a preservative and in industrial applications as a corrosion inhibitor. Additionally, it serves as an intermediate in organic synthesis and as a laboratory reagent.
Q: How does Sodium Salicylate differ from aspirin?
A: While both compounds are derived from salicylic acid, Sodium Salicylate is the sodium salt form which makes it more water-soluble than aspirin (acetylsalicylic acid). Sodium Salicylate is less likely to cause stomach irritation compared to aspirin but has similar therapeutic effects at equivalent doses. The choice between them depends on specific application requirements and patient tolerance.
Q: What safety precautions should be taken when handling Sodium Salicylate?
A: Always wear appropriate personal protective equipment including gloves and safety glasses. Avoid inhalation of dust and prevent contact with eyes and skin. In case of accidental exposure, rinse immediately with plenty of water. Store in a cool, dry place away from strong oxidizers. Follow all local regulations for chemical handling and disposal.
Applications
Sodium Salicylate finds applications in multiple industries:
- Pharmaceutical: Used in analgesic and anti-inflammatory medications
- Cosmetic: Acts as preservative and exfoliant in skincare products
- Industrial: Serves as corrosion inhibitor in metal treatment processes
- Laboratory: Used as reagent in various chemical analyses
- Food: Approved as preservative in certain food products (limited use)
Storage and Handling
Proper storage conditions for Sodium Salicylate:
| Condition | Requirement |
|---|---|
| Temperature | 15-30°C (59-86°F) |
| Humidity | ≤65% RH |
| Light | Protect from direct sunlight |
| Container | Tightly sealed, moisture-proof |
| Shelf Life | 36 months from production date |
When handling Sodium Salicylate in bulk quantities, ensure proper ventilation in the working area and use dust control measures to prevent airborne dispersion.
Regulatory Information
Sodium Salicylate is regulated under various international standards:
- United States Pharmacopeia (USP) grade available
- European Pharmacopoeia (Ph. Eur.) compliance
- Listed in FDA Inactive Ingredients Guide
- REACH registered in Europe
- Meets ISO 9001 quality management standards
Always check local regulations before using Sodium Salicylate in specific applications as requirements may vary by country and intended use.