Ethyl acetoacetate
Ethyl Acetoacetate: Premium Chemical Solution for Your Industrial Needs
Ethyl acetoacetate (EAA) is a versatile organic compound widely used in pharmaceuticals, agrochemicals, dyes, and flavoring agents. As a leading manufacturer and supplier, we provide high-purity ethyl acetoacetate that meets international quality standards.
Key Specifications of Our Ethyl Acetoacetate:
- Chemical Formula: C6H10O3
- CAS Number: 141-97-9
- Molecular Weight: 130.14 g/mol
- Appearance: Colorless to slightly yellow liquid
- Odor: Fruity, pleasant ester-like
- Purity: ≥99.0% (GC analysis)
Technical Parameters:
| Property | Value |
|---|---|
| Boiling Point | 180-181°C (356-358°F) |
| Melting Point | -45°C (-49°F) |
| Density | 1.028 g/cm³ at 20°C |
| Flash Point | 84°C (183°F) |
| Refractive Index | 1.418-1.420 at 20°C |
| Solubility | Miscible with ethanol, ether; slightly soluble in water |
| Vapor Pressure | 0.3 mmHg at 20°C |
Quality Control Standards:
| Test Item | Specification | Test Method |
|---|---|---|
| Assay (GC) | ≥99.0% | ASTM E260-96 |
| Water Content | ≤0.1% | Karl Fischer |
| Acidity (as CH3COOH) | ≤0.05% | Titration |
| Residue on Evaporation | ≤0.01% | Gravimetric |
Packaging Options:
- Drums: 200kg net weight in galvanized iron drums
- Intermediate Bulk Containers (IBC): 1000kg capacity
- ISO Tanks: 20,000kg capacity
- Custom Packaging: Available upon request
Storage & Handling:
Store ethyl acetoacetate in tightly closed containers in a cool, dry, well-ventilated area away from heat sources and oxidizing agents. Recommended storage temperature: 15-25°C (59-77°F).
Ethyl Acetoacetate FAQ Section:
Q: What are the main industrial applications of ethyl acetoacetate?
A: Ethyl acetoacetate serves as a crucial intermediate in numerous industries. In pharmaceuticals, it's used in synthesizing antipyretics, analgesics, and antimalarial drugs. The agrochemical industry utilizes it for producing pesticides and herbicides. It's also essential in dye manufacturing, perfumery, and as a flavoring agent in food products (typically in very small quantities).
Q: What safety precautions should be taken when handling ethyl acetoacetate?
A: While ethyl acetoacetate is generally stable, proper safety measures should be followed. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas. In case of skin contact, wash thoroughly with soap and water. For eye contact, flush immediately with plenty of water for at least 15 minutes and seek medical attention. Keep away from heat, sparks, and open flames due to its combustible nature.
Q: What is the shelf life of ethyl acetoacetate and how can I ensure product quality?
A: Ethyl acetoacetate typically has a shelf life of 24 months when stored properly in sealed containers under recommended conditions. To maintain quality, store in original containers away from direct sunlight and moisture. Avoid contamination with water or other chemicals. Regular quality checks including purity analysis can help verify product integrity over time.
Additional Product Information:
Our ethyl acetoacetate production follows strict GMP guidelines with multiple quality checkpoints throughout manufacturing. We conduct rigorous batch testing to ensure consistency and purity. Technical support is available to assist with application development and troubleshooting.
For specialized requirements, we offer custom synthesis of ethyl acetoacetate derivatives with modified properties. Our R&D team can collaborate on developing tailored solutions for specific industrial applications.
Why Choose Our Ethyl Acetoacetate:
- Consistent high purity (≥99.0%)
- Competitive global pricing
- Flexible packaging options
- Reliable supply chain with on-time delivery
- Comprehensive technical documentation
- Dedicated customer support
Q: Is ethyl acetoacetate biodegradable and what are its environmental impacts?
A: Ethyl acetoacetate shows moderate biodegradability in standard tests. While not classified as highly toxic to aquatic life, it should be prevented from entering waterways. In case of spills, contain the material using absorbents and dispose according to local regulations. Industrial users should implement proper waste management procedures to minimize environmental impact.
Q: Can ethyl acetoacetate be shipped internationally and what regulations apply?
A: Yes, ethyl acetoacetate can be shipped globally with proper documentation. It's classified as a flammable liquid (Packing Group III) for transport purposes. Required documentation typically includes Safety Data Sheets (SDS), product specifications, and transport declarations. Specific regulations may vary by country or region (such as REACH in Europe or TSCA in the United States). Our logistics team ensures all shipments comply with applicable regulations.
Q: What analytical methods are used to verify ethyl acetoacetate quality?
A: We employ multiple analytical techniques to verify ethyl acetoacetate quality. Gas chromatography (GC) is the primary method for purity determination. Other tests include Karl Fischer titration for water content, refractive index measurement, and acid value determination. Each batch is thoroughly analyzed and comes with a Certificate of Analysis detailing all test results.
Chemical Reactions and Derivatives:
Ethyl acetoacetate is valued for its reactivity and serves as a building block for various chemical transformations:
- Keto-enol tautomerism: Exists in equilibrium between keto and enol forms
- Alkylation: Forms substituted derivatives at the alpha position
- Acid hydrolysis: Produces acetone and carbon dioxide
- Condensation reactions: Forms heterocyclic compounds with various reagents
Q: What is the difference between ethyl acetoacetate and methyl acetoacetate?
A: The main difference lies in the ester group - ethyl acetoacetate has an ethyl ester (C2H5O-) while methyl acetoacetate has a methyl ester (CH3O-). This affects properties like boiling point (methyl derivative boils at 170°C vs 180°C for ethyl) and solubility. Reactivity is similar but may vary in specific applications. The choice between them depends on the desired reaction products and process conditions.
Q: How stable is ethyl acetoacetate under different temperature conditions?
A: Ethyl acetoacetate demonstrates good thermal stability under normal storage conditions. However, prolonged exposure to temperatures above 50°C (122°F) may lead to decomposition. Below -45°C (-49°F), it solidifies but regains its liquid form and properties upon warming without significant degradation. For long-term storage, maintain between 15-25°C (59-77°F).
Q: Can ethyl acetoacetate be used in food applications?
A: Ethyl acetoacetate is approved as a flavoring agent in some food applications, typically in very small quantities (usually less than 0.1%). However, food-grade specifications are more stringent than industrial grades. For food use, special purification processes are required to meet regulatory standards. Always verify compliance with local food safety regulations before use in food products.