Phenylacetyl chloride
Phenylacetyl Chloride: High-Quality Chemical Solutions for Industrial Applications
Phenylacetyl chloride is a versatile organic compound widely used in pharmaceutical, agrochemical, and specialty chemical industries. As a leading supplier, we offer premium-grade phenylacetyl chloride with strict quality control measures to ensure optimal performance in your applications.
Product Specifications
- Chemical Name: Phenylacetyl chloride
- CAS Number: 103-80-0
- Molecular Formula: C8H7ClO
- Molecular Weight: 154.59 g/mol
- Appearance: Colorless to pale yellow liquid
- Purity: ≥98% (GC analysis)
- Density: 1.168 g/cm³ at 25°C
- Boiling Point: 105-107°C at 15 mmHg
- Flash Point: 93°C
Packaging Options
| Package Size | Material | Special Features |
|---|---|---|
| 100g | Amber glass bottle | Tamper-proof seal |
| 500g | HDPE container | Moisture barrier |
| 1kg | Steel drum | Corrosion-resistant lining |
| 25kg | High-grade plastic drum | Double containment |
Frequently Asked Questions About Phenylacetyl Chloride
What are the primary applications of phenylacetyl chloride?
Phenylacetyl chloride serves as a crucial intermediate in organic synthesis. Its main applications include pharmaceutical manufacturing (particularly in penicillin production), agrochemical formulations, and specialty chemical synthesis. The compound's reactive acyl chloride group makes it valuable for introducing the phenylacetyl moiety into various molecular structures.
How should phenylacetyl chloride be stored for maximum stability?
For optimal storage conditions, phenylacetyl chloride should be kept in tightly sealed containers under inert atmosphere (nitrogen or argon) at temperatures between 2-8°C. The storage area should be dry, well-ventilated, and protected from moisture. Under these conditions, phenylacetyl chloride typically maintains stability for 12-24 months from production date.
What safety precautions are necessary when handling phenylacetyl chloride?
Phenylacetyl chloride requires careful handling due to its corrosive nature and moisture sensitivity. Always use appropriate PPE including chemical-resistant gloves, goggles, and lab coat. Work should be conducted in a fume hood with proper ventilation. In case of skin contact, immediately flush with copious amounts of water for at least 15 minutes and seek medical attention. The compound reacts violently with water, releasing HCl gas, so moisture must be strictly avoided during handling.
Technical Data Sheet
| Parameter | Specification | Test Method |
|---|---|---|
| Assay (GC) | ≥98% | ASTM E260 |
| Water Content | ≤0.5% | Karl Fischer |
| Free Chloride | ≤1.0% | Argentometric |
| Color (APHA) | ≤50 | ASTM D1209 |
| Refractive Index | 1.5320-1.5340 | ASTM D1218 |
Industrial Applications
- Pharmaceuticals: Key intermediate for semisynthetic penicillins
- Agrochemicals: Building block for pesticide formulations
- Fragrance Industry: Precursor for phenylacetic acid derivatives
- Research & Development: Versatile reagent for organic synthesis
Handling and Transportation
Phenylacetyl chloride is classified as a Class 8 Corrosive substance for transportation purposes (UN 3265). All shipments comply with IMDG/IATA/ADR regulations. Our packaging solutions are designed to prevent leakage and moisture ingress during transit. For international shipments, we provide complete documentation including SDS, Certificate of Analysis, and customs declarations.
Additional Phenylacetyl Chloride Information
Chemical Properties
Phenylacetyl chloride (C6H5CH2COCl) is an aromatic acyl chloride characterized by its sharp, pungent odor. The molecule consists of a phenyl group attached to an acetyl chloride functional group, making it highly reactive toward nucleophiles. This reactivity profile enables its use in various acylation reactions under mild conditions.
Synthesis Methods
Industrial production of phenylacetyl chloride typically involves the reaction of phenylacetic acid with thionyl chloride or oxalyl chloride. The process requires careful temperature control and yields high-purity product after fractional distillation. Our manufacturing facilities utilize state-of-the-art reaction monitoring systems to ensure consistent quality batch after batch.
Regulatory Compliance
Our phenylacetyl chloride meets all relevant international standards including REACH, USP, and EP specifications. We maintain comprehensive documentation for regulatory compliance and can provide customized certificates to meet specific customer requirements. The product is manufactured in ISO 9001-certified facilities with strict adherence to cGMP guidelines.
Why Choose Our Phenylacetyl Chloride?
- Consistent high purity (≥98%) verified by rigorous QC testing
- Competitive pricing with volume discounts available
- Flexible packaging options to suit your requirements
- Technical support from experienced chemists
- Reliable global shipping with temperature-controlled options
- Custom synthesis and packaging available
For inquiries about phenylacetyl chloride pricing, technical specifications, or custom formulations, please contact our sales team. We're committed to providing high-quality chemical solutions tailored to your specific needs.